Aerogel Research Laboratory was established in 1996 to investigate fundamental properties as well as cutting-edge applications of aerogels. Aerogel materials have the lowest thermal conductivity, lowest dieletric constant, lowest speed of sound, and lowest density of any solid material. Applications include: thermal/acoustic/electrical insulation, microanalytical instrumentation, sensors, and sub-atomic collection media.

Aerospace Research Laboratory was established in 1986 to conduct basic and applied research in advanced aerospace technologies. Research interests have expanded to include high-speed mixing and combustion, aeroacoustics, structures and materials, optical techniques, microscale heat transfer, and computational modeling.

Bio-Thermal-Fluid-Mechanics Laboratory was established to investigate highly interdisciplinary problems, both fundamental and applied, relating to laminar and turbulent flows, heat and mass transfer in biological, engineering and medical systems ranging in size from a few nanometers to tens of meters. Experimental, theoretical and numerical modeling activities range from the development of innovative biomedical devices such as catheters for the treatment of neurological and cardiovascular diseases, to the understanding of sensors and sensing in nature with engineering applications in mind, to flow-structure interactions in the aorta and in computer hard disk drives.

Cardiac Systems Biology Lab focuses on the study of cell signaling networks. Perturbations in these signaling networks contribute to the pathogenesis of many diseases, including cardiovascular disease, cancer and diabetes. One explanation for the remarkable ability of complex signaling networks to control the cell is the use of temporal and spatial strategies, such as feedback and compartmentation. Understanding of these sophisticated control mechanisms will require an integration of experimental and computational systems biology.

Center for Applied Biomechanics is dedicated to vehicle safety testing with a major emphasis on studying impact and injury biomechanics. The focal point of the 10,000 square foot facility is a test sled mounted on a 66-foot track which allows simulation of high speed automobile crashes. In addition to the sled system, the CAB has a number of pneumatic and gravity driven impactors as well as state-of-the-art high speed data acquisition and digital video systems. Major research efforts at the laboratory include the study of advanced occupant restraint systems including air bag and seat belt systems. In particular, the CAB is establishing guidelines and criteria for the mitigation of airbag induced injuries.

Center for Electrochemical Science and Engineering (CESE) is a multi-disciplinary research effort that incorporates the departments of Materials Science and Engineering, and Chemical Engineering, as well as interactions with Electrical and Computer Engineering, Computer Science, and Physics. One of the nation's leading research groups of its kind, its research affects the performance and reliability of most products manufactured in the world today.

Center for In-Vivo Hyperpolarized Gas MR Imaging is a promising option for medical imaging of air spaces and certain tissues in humans without exposing patients to radiation associated with other methods (high resolution Computed Tomography and V/Q techniques, for example.) Since spring of 1996, UVa Departmental Research Team for Hyperpolarized Gases has been exploring and conducting research in this field.

Center for Risk Management of Engineering Systems was founded by the University of Virginia in 1987 as a University-wide resource. It develops theory, methodology, and technology to assist in the management of risk for a variety of engineering systems. Working closely with faculty and students at the Center, industry and government sponsors of research contribute their unique strengths and interests.

Center for Semicustom Integrated Systems is an internationally respected research group in the areas of computer engineering and digital systems. The Center's ultimate missions are to accelerate economic growth, to improve products and processes, and to integrate the results of academic research into Very Large-Scale Integration (VLSI) industry developments. Its research and education programs help satisfy the growing need for leading-edge design tools and methods in the VLSI industry.

Center for Transportation Studies focuses on issues and problems related to the development, operation, and maintenance of a safe, efficient intermodal transportation system for the Commonwealth of Virginia and the nation. The Center's research program is noted for being responsive to emerging challenges from the transportation sector and for continually probing into new areas of transportation-related research. The Center's comprehensive research program covers areas such as intelligent transportation systems, transportation planning and logistics, traffic simulation, highway safety, transportation pavements, and freight and traffic operations.

Computational Systems Biology Laboratory (CSBL) at the University of Virginia develops methods for integrating high-throughput data of biological systems and characterizing cellular network properties relevant to human disease. In particular, we reconstruct integrated cellular signaling networks and develop tools to analyze their properties. The analysis of these networks requires high-performance computing capabilities and sophisticated mathematical techniques.

Dependability Research Group studies the survivability of critical information systems-air traffic control, telecommunications, nationwide control of power distribution, and the financial system. Societal dependence on these systems is growing and will continue to do so for the foreseeable future. The Center's research focuses on designing software which can be tailored to information systems to ensure the intended operation of their existing components.

The Energy Initiative at the University of Virginia is dedicated to developing and commercializing new sources of energy and new techniques to preserve and reclaim vital resources. The University of Virginia's School of Engineering and Applied Science is partnering with other U.Va. schools to facilitate this innovation. University faculty, researchers and students are contributing to energy technology research — research that includes work in the areas of alternative renewable resources, ethics, policy, fuel cell efficiencies, nanotechnology, solar energy, and sustainable and efficient housing.

High-Performance Low-Power (HPLP) VLSI Laboratory focuses primarily on original research in the field of low power and high performance electronics, spanning digital VLSI and analog systems, architectures, circuits, and algorithms. HPLP currently has eight active researchers, as well as a new lab facility containing PCs and workstations donated by IBM and Intel.

Human Computer Interaction develops decision-aiding systems, training systems and models of human performance in a wide variety of domains such as process control, medical, military and transportation. Teams of people typically work together and with a variety of computational systems to meet objectives within a complex set of constraints using both well-defined strategies and ad-hoc reasoning. Typical tasks to be supported, trained, or modeled include monitoring, diagnosis, control, scheduling, planning, and problem-solving for individuals, teams, and organizations.

Intelligent Processing of Materials Laboratory (IPML) is one of the nation's premier centers for research on the processing of advanced materials. Affiliated with the University's School of Engineering and Applied Sciences, the laboratory incorporates both the synthesis and processing of materials along with their modeling, sensing, and control. Goals of IPML's research include development of innovative process technologies, creating models for predicting materials evolution during processing, designing advanced in-situ sensors for tracking material changes during processing, and creating model-based path optimization and feedback control.

Internet Commerce Group, InterCom, is a coalition of university faculty and business leaders that promotes development of electronic commerce in Virginia by providing technical and business software, training, and consulting services to companies entering (or already participating in) the electronic marketplace.

Laboratory for Atomic and Surface Physics (LASP) is one of the world's leading laboratories studying the interaction of energetic particles (ions, electrons) UV photons and laser beams with surfaces. It seeks to understand the mechanisms leading to electronic excitations (luminescence, emission of electrons, radiation, atoms and molecules (sputtering), and to radiation damage, chemical changes or heat. The studies use a wide array of experimental techniques such as infrared spectroscopy, microbalance, mass spectrometry, and surface analyis and also computer simulations. The research has applications in semiconductor processing, nuclear fusion, gas discharges, biology, astrophysics, and space exploration. A substantial part of the laboratory's work consists in modeling and simulations of surface processes in icy satellites, planetary atmospheres and magnetospheres, and interstellar grains. Projects are supported by NASA, NSF, and SWRI. LASP collaborates with industrial, University, and government laboratories in the US and several countries overseas to advance research and education in this field.

Laboratory for Computer Architecture at Virginia (LAVA) focuses on processor-design issues, especially multi-core and multi-threaded chip architectures, architectures for temperature-aware and power-aware computing; applications of control theory to computer architecture; graphics architecture; novel processor organizations; and associated questions of modeling technique. The LAVA Lab currently receives funding from NSF, ARO, Intel and IBM and has ongoing collaborations with Harvard and IBM TJ Watson.

Ley Lab is part of the Department of Biomedical Engineering, and focuses on molecular mechanisms of atherosclerosis, biomechanics of leukocyte adhesion and targeted ultrasound contrast agents, molecular mechanisms of inflammation in Crohn's disease, molecular mechanisms of neutrophil recruitment to the lung, and neutrophil homeostasis and proliferation in inflammation.

MAE Design Lab provides specialized computer resources and workspace for students in the Department of Mechanical and Aerospace Engineering. The Lab is focused on research and design projects of graduate students and upper-level undergraduates.

Microscale Heat Transfer Laboratory is dedicated to developing new techniques to assist in measuring, understanding, and utilizing microscale thermal phenomena. The laboratory's research is aimed at developing a fundamental understanding of energy transport on ultra short time and length scales.

Molecular Biomechanics Laboratory, part of the Department of Biomedical Engineering, is dedicated to understanding the molecular mechanisms by which cells move, and the application of this knowledge to the improvement of American public health.

MRSEC Center for Nanoscopic Materials Design explores new directions in the nanoscale design and control of self-assembled epitaxial semiconductor quantum dots by providing new algorithms for understanding and controlling the coupling of short, medium and long range order in these structures. The Center collaborates with industrial, University, and government laboratories to support and further materials research and education in this field.

Multiscale Muscle Mechanics Lab identifies the principles of muscle design by characterizing the relationships between muscle structure, mechanical properties, biology, and function. The lab integrates a variety of computational and experimental approaches to achieve this goal, and applies these findings to understanding and improving treatments for musculoskeletal impairments.

Nanoscale Materials Characterization Facility (NMCF) provides imaging, diffraction and chemical analysis of materials from atomic to microscopic levels, and offers guidance to individuals wanting to conduct their own analyses. The NMCF houses three transmission electron microscopes (TEMs), two scanning electron microscopes (SEMs), a focused Ga+ ion beam (FIB) microscope, extensive hardware/software for image simulation, processing and analysis, and a variety of specimen preparation equipment. The facility also has three X-ray diffractometers (XRD's) with a variety of capabilities and software for data analysis.

NanoQuEST: Institute for Nanoscale & Quantum Engineering, Science & Technology. A university-wide institute that spearheads cutting edge research and educational programs on nanoscale engineering and quantum manipulation within the atom, for applications including nanoelectronics, biomedical engineering, and catalysis. With seventy faculty members across multiple departments and schools at the university with nanoscience research programs, the institute seeks to develop excellence in thrust areas such as: engineering of electron charge and spin, controlling biological functions within living cells, developing multifunctional nanostructured systems, controlling nanoscale dynamics, and nanoscale control of chemical reactions. These thrusts are enabled through a research and educational infrastructure developed through the institute. An estimated 25 graduate students complete their theses each year in these projects.

Next Generation Real-Time Computing Lab is part of the Computer Science Department at the University of Virginia. The laboratory studies a wide range of issues in all aspects of real-time computing and wireless networks. Real-time principles are becoming important for all systems since audio and video streams are being utilized in many new contexts from control applications to the Next Generation Internet.

Peirce-Cottler Laboratory at the University of Virginia uses a parallel approach that combines experimental models with agent-based computational models to guide new approaches in tissue engineering. We are particularly interested in the microcirculatory system and how microvascular networks structurally adapt, through active growth and remodeling. These processes are relevant to a variety of diseases and pathologies, including heart disease, peripheral limb ischemia, cancer, and diabetes.

Predictive Technology Lab was created to support the information technology needs of law enforcement agencies throughout the Commonwealth of Virginia and on a national level. The Institute is funded by national funding agencies including the Virginia Department of Criminal Justice Services, and the National Institute of Justice's Crime Mapping Research Center.

Robert M. Berne Cardiovascular Research Center is an evolving organization based on the voluntary scientific interactions of investigative faculty with a broad interest in research in diseases of the cardiovascular system. It is a lightening rod, attracting ongoing research in cardiovascular function, as well as stimulating new initiatives. The Center is designed to be able to respond quickly to exciting new research opportunities, by providing financial and administrative assistance. Such assistance offers innovative investigators the possibility to adapt rapidly to new directions in their research programs, a capability that becomes ever more important as the pace of technology places greater importance on rapid reaction to scientific opportunity. The Center is also dedicated to working with the faculty in making the University a center of state-of-the-art technological excellence.

Rotating Machinery and Controls Laboratory (ROMAC) conduct research in the areas of rotor dynamics, turbomachinery, structural dynamics, magnetic bearings, automatic controls, turbomachinery flows, fluid film bearings, and seals. The Laboratory's research is supported by a consortium of industries through the ROMAC Industrial Research Program.

Science and Engineering of Laser Interactions with Matter (SELIM) graduate training program is designed to develop students with enhanced mastery and appreciation of the knowledge and state-of-the-art technical skills required for rapid advancements in modern science and technology.

Smart Travel Lab is a state-of-the-art facility that supports research and education in the rapidly emerging area of intelligent transportation systems (ITS). Current projects include investigating potential benefits of vehicle infrastructure integration-enabled ramp metering as well as evaluation of advanced traffic signal controllers using hardware in the loop simulation.

Space Physics and Surface Physics Theory Program studies the physics and chemistry of energetic ion, electron and uv-photon interactions with surfaces and gases. the processes of interest are desorption and sputtering, as well as the radiolysis and photolysis of surfaces and gases. the motivation for the program's research is to understand problems in space physics and astronomy.

Surface Science Center provides services on surface analysis, including modifying the surface layers of materials by ion implantation, and surface characterization and depth profiling of sample compositions using a Perkin-Elmer 560 system. Available techniques are Angle-resolved X-Ray Photoelectron Spectroscopy (XPS or ESCA), Scanning Auger Electron Microscopy with sub-micron resolution, Ultraviolet Photoelectron Spectroscopy (UPS), Secondary Ion Mass Spectrometry (SIMS), Ion Scattering Spectroscopy (ISS) and Fourier Transform Infrared Spectroscopy (FTIR). Each technique can be combined with the others and with sputter etching (using a differentially pumped ion gun) to obtain composition depth profiles.

Traffic Operations Lab (TOL) is part of the Center for Transportation Studies of Civil Engineering Department. TOL supports research and education related to traffic signal control, optimization, and simulation and is equipped with the state-of-the-art traffic signal controllers and microscopic simulation programs, as well as hardware in the loop simulation (HILS) system. The HILS system allows testing of advanced features of actual traffic signal controllers within a laboratory environment. TOL has access to real-time traffic data from the VDOT traffic control systems through the Smart Travel Laboratory. TOL research mainly focuses on applications of advanced statistical techniques and optimization methods for developing traffic signal control algorithms and improving calibration and validation procedure for microscopic simulation models.

University of Virginia Microfabrication Laboratories (UVML) serves as the University's center for research and devlopment in solid-state materials, devices, and circuits. This laboratory, formed from the AEpL laboratories (which was founded in 1967), has a 3,500 square-foot clean room facility for device fabrication and materials growth, as well as a variety of other facilities for microwave and optical analysis, device design, testing and packaging. The UVML operates out of the Charles Brown Department of Electrical and Computer Engineering, but is open to and used by numerous other Departments in the University.

University of Virginia Program on Secure and Dependable Computing seeks to assure the trustworthy operation of complex software-intensive systems in a holistic, multi-disciplinary manner. The program seeks end-to-end architectural solutions grounded in an end-to-end understanding of software, systems, and human, social and organizational control and practices.

Virginia Center for Grid Research is dedicated to performing research and solving issues surrounding the operation, deployment, and use of large distributed data and computing systems. Research covers a wide spectrum of activities including pure computer science/engineering research, grid system development and deployment, grid research community interaction, development of standards, and end user collaboration and outreach.

The Virginia Transportation Research Council is a partnership of the Virginia Department of Transportation and the University of Virginia, created in 1948. It conducts a comprehensive program of engineering, planning and policy research for all of Virginia's transportation agencies and ranks among the nation's most highly regarded transportation research institutes. The Research Council supports U.Va. faculty and students through cooperative research projects as well as through the Smart Travel Lab in the Center for Transportation Studies; VTRC scientists also comprise the faculty for the graduate pavements program in the Civil and Environmental Engineering Department.